Intravitreal bevacizumab in pigmented rabbit eyes: histological analysis 90 days after injection Bevacizumabe intravítreo em olhos de coelhos não albinos: análise histológica 90 dias após a injeção

Intravitreal bevacizumab in pigmented rabbit eyes: histological analysis 90 days after injection Bevacizumabe intravítreo em olhos de coelhos não albinos: análise histológica 90 dias após a injeção

PURPOSE: To evaluate bevacizumab toxicity in neurosensorial retina and retinal pigment epithelium in pigmented rabbit eyes by means of histological studies. METHODS: Thirty eyes of fifteen rabbits were distributed into three groups: sham group (S), that received a 0.1 ml balanced saline solution (BS...

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Bibliographic Details
Main Authors: João Carlos Diniz Arraes, Roberto Carlos Tedesco, Tatiana Azevedo Arraes, Elilson Batista da Silva, Alexandre Ventura, Marcos Pereira de Ávila
Format: Article
Language:English
Published: Conselho Brasileiro de Oftalmologia 2009-10-01
Series:Arquivos Brasileiros de Oftalmologia
Subjects:
Inibidores da angiogênese
Degeneração macular
Neovascularização patológica
Macula lutea
Injeções
Retina
Coelhos
Modelos animais
Angiogenesis inhibitors
Macular degeneration
Neovascularization
pathologic
Injections
Rabbits
Models, animal
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492009000500011

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492009000500011

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