In vivo generation of immature inner hair cells in neonatal mouse cochleae by ectopic Atoh1 expression.

Regeneration of auditory hair cells (HCs) is a promising approach to restore hearing. Recent studies have demonstrated that induced pluripotent stem cells/embryonic stem cells or supporting cells (SCs) adjacent to HCs can be converted to adopt the HC fate. However, little is known about whether new...

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Bibliographic Details
Main Authors: Zhiyong Liu, Jie Fang, Jennifer Dearman, Lingli Zhang, Jian Zuo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3930725?pdf=render