Unsymmetrical Bisquinolines with High Potency against <i>P. falciparum</i> Malaria

Quinoline-based scaffolds have been the mainstay of antimalarial drugs, including many artemisinin combination therapies (ACTs), over the history of modern drug development. Although much progress has been made in the search for novel antimalarial scaffolds, it may be that quinolines will remain use...

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Bibliographic Details
Main Authors: Katherine M. Liebman, Steven J. Burgess, Bornface Gunsaru, Jane X. Kelly, Yuexin Li, Westin Morrill, Michael C. Liebman, David H. Peyton
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
SAR
Online Access:https://www.mdpi.com/1420-3049/25/9/2251