Errata. PCSK9 function and physiology1

PCSK9 has exploded onto center stage of plasma cholesterol metabolism, raising hopes for a new strategy to treat hypercholesterolemia. PCSK9 in a plasma protein that triggers increased degradation of the LDL receptor. Gain-of-function mutations in PCSK9 reduce LDL receptor levels in the liver, resul...

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Bibliographic Details
Main Authors: Andrew S. Peterson, Loren G. Fong, Stephen G. Young
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520347313