Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates.

Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates.

BACKGROUND:The var2csa gene encodes a Plasmodium falciparum adhesion receptor which binds chondroitin sulfate A (CSA). This var gene is more conserved than other PfEMP1/var genes and is found in all P. falciparum isolates. In isolates 3D7, FCR3/It4 and HB3, var2csa is transcribed from a sub-telomeri...

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Bibliographic Details
Main Authors: Adam F Sander, Ali Salanti, Thomas Lavstsen, Morten A Nielsen, Pamela Magistrado, John Lusingu, Nicaise Tuikue Ndam, David E Arnot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2723927?pdf=render

Internet

http://europepmc.org/articles/PMC2723927?pdf=render

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