Hi-JAKi-ng Synovial Fibroblasts in Inflammatory Arthritis With JAK Inhibitors

Hi-JAKi-ng Synovial Fibroblasts in Inflammatory Arthritis With JAK Inhibitors

The Janus kinase (JAK)—Signal transducer and activator of transcription (STAT) pathway is one of the central signaling hubs in inflammatory, immune and cancer cells. Inhibiting the JAK-STAT pathway with JAK inhibitors (jakinibs) constitutes an important therapeutic strategy in cancer and chronic inf...

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Bibliographic Details
Main Authors: Blaž Burja, Tonja Mertelj, Mojca Frank-Bertoncelj
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Medicine
Subjects:
synovial fibroblasts
fibroblast-like synoviocytes
JAK inhibitors
STATs
rheumatoid arthritis
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00124/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00124/full

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