Phosphorylation of different tau sites during progression of Alzheimer’s disease

Phosphorylation of different tau sites during progression of Alzheimer’s disease

Abstract Alzheimer’s disease is characterized by accumulation of amyloid plaques and tau aggregates in several cortical brain regions. Tau phosphorylation causes formation of neurofibrillary tangles and neuropil threads. Phosphorylation at tau Ser202/Thr205 is well characterized since labeling of th...

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Bibliographic Details
Main Authors: Joerg Neddens, Magdalena Temmel, Stefanie Flunkert, Bianca Kerschbaumer, Christina Hoeller, Tina Loeffler, Vera Niederkofler, Guenther Daum, Johannes Attems, Birgit Hutter-Paier
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Acta Neuropathologica Communications
Subjects:
Microtubule-associated protein tau
Phosphorylation
Cingulate
Frontal
Occipital and temporal cortex
Transentorhinal region
Online Access:http://link.springer.com/article/10.1186/s40478-018-0557-6

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http://link.springer.com/article/10.1186/s40478-018-0557-6

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