High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production

Measurement(s) nascent RNA • Image • S phase • nucleolus organization • Cellular Morphology • Cell Cycle Phase Technology Type(s) metabolic labelling: 5-ethynyl uridine • spinning-disk confocal microscope • supervised machine learning • Image Processing Factor Type(s) gene expression Sample Characte...

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Bibliographic Details
Main Authors: Micha Müller, Lucas Pelkmans, Scott Berry
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-021-00944-5