A single amino acid change converts the sugar sensor SGLT3 into a sugar transporter.
Sodium-glucose cotransporter proteins (SGLT) belong to the SLC5A family, characterized by the cotransport of Na(+) with solute. SGLT1 is responsible for intestinal glucose absorption. Until recently the only role described for SGLT proteins was to transport sugar with Na(+). However, human SGLT3 (hS...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-04-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2857651?pdf=render |