Dauricine Attenuates Spatial Memory Impairment and Alzheimer-Like Pathologies by Enhancing Mitochondrial Function in a Mouse Model of Alzheimer's Disease

Dauricine Attenuates Spatial Memory Impairment and Alzheimer-Like Pathologies by Enhancing Mitochondrial Function in a Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is characterized by extracellular amyloid plaques composed of β-amyloid (Aβ) and intracellular neurofibrillary tangles containing hyperphosphorylated tau protein. No effective therapy is available for this disease. In this study, we investigated the potential therapeuti...

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Bibliographic Details
Main Authors: Chongyang Chen, Pan Liu, Jing Wang, Haitao Yu, Zaijun Zhang, Jianjun Liu, Xiao Chen, Feiqi Zhu, Xifei Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Alzheimer's disease
dauricine
proteomics
mitochondrial function
synaptic function
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.624339/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.624339/full

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