Glycine inhibitory dysfunction turns touch into pain through PKCgamma interneurons.

Dynamic mechanical allodynia is a widespread and intractable symptom of neuropathic pain for which there is a lack of effective therapy. During tactile allodynia, activation of the sensory fibers which normally detect touch elicits pain. Here we provide a new behavioral investigation into the dynami...

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Bibliographic Details
Main Authors: Loïs S Miraucourt, Radhouane Dallel, Daniel L Voisin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2043493?pdf=render