HTLV-1 propels thymic human T cell development in "human immune system" Rag2⁻/⁻ gamma c⁻/⁻ mice.

HTLV-1 propels thymic human T cell development in "human immune system" Rag2⁻/⁻ gamma c⁻/⁻ mice.

Alteration of early haematopoietic development is thought to be responsible for the onset of immature leukemias and lymphomas. We have previously demonstrated that Tax(HTLV-1) interferes with ß-selection, an important checkpoint of early thymopoiesis, indicating that human T-cell leukemia virus type...

Full description

Bibliographic Details
Main Authors: Julien Villaudy, Mélanie Wencker, Nicolas Gadot, Nicolas A Gillet, Jean-Yves Scoazec, Louis Gazzolo, Markus G Manz, Charles R M Bangham, Madeleine Duc Dodon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21909275/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21909275/?tool=EBI

Similar Items