Sex influences eQTL effects of SLE and Sjögren’s syndrome-associated genetic polymorphisms

Sex influences eQTL effects of SLE and Sjögren’s syndrome-associated genetic polymorphisms

Abstract Background Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) are autoimmune disorders characterized by autoantibodies, dysregulated B cells, and notably high female-to-male incidence ratios. Genome-wide association studies have identified several susceptibility SNPs fo...

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Bibliographic Details
Main Authors: Magdalena Lindén, Jorge I. Ramírez Sepúlveda, Tojo James, Gudny Ella Thorlacius, Susanna Brauner, David Gómez-Cabrero, Tomas Olsson, Ingrid Kockum, Marie Wahren-Herlenius
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Biology of Sex Differences
Subjects:
Sjögren’s syndrome
SLE
Autoimmunity
Sex difference
eQTL
Online Access:http://link.springer.com/article/10.1186/s13293-017-0153-7

Internet

http://link.springer.com/article/10.1186/s13293-017-0153-7

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