Activation of TRPA1 by membrane permeable local anesthetics

<p>Abstract</p> <p>Background</p> <p>Low concentrations of local anesthetics (LAs) suppress cellular excitability by inhibiting voltage-gated Na<sup>+ </sup>channels. In contrast, LAs at high concentrations can be excitatory and neurotoxic. We recently demon...

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Bibliographic Details
Main Authors: Kronewald Sergej, Lattrell Anja, Leffler Andreas, Niedermirtl Florian, Nau Carla
Format: Article
Language:English
Published: SAGE Publishing 2011-08-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/7/1/62