TLR accessory molecule RP105 (CD180) is involved in post-interventional vascular remodeling and soluble RP105 modulates neointima formation.

<h4>Background</h4>RP105 (CD180) is TLR4 homologue lacking the intracellular TLR4 signaling domain and acts a TLR accessory molecule and physiological inhibitor of TLR4-signaling. The role of RP105 in vascular remodeling, in particular post-interventional remodeling is unknown.<h4>...

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Main Authors: Jacco C Karper, Mark M Ewing, Margreet R de Vries, Saskia C A de Jager, Erna A B Peters, Hetty C de Boer, Anton-Jan van Zonneveld, Johan Kuiper, Eric G Huizinga, T Harma C Brondijk, J Wouter Jukema, Paul H A Quax
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23844130/pdf/?tool=EBI