Functional analysis of conserved motifs in influenza virus PB1 protein.

The influenza virus RNA polymerase complex is a heterotrimer composed of the PB1, PB2, and PA subunits. PB1, the catalytic core and structural backbone of the polymerase, possesses four highly conserved amino acid motifs that are present among all viral RNA-dependent RNA polymerases. A previous stud...

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Bibliographic Details
Main Authors: Caroline Chu, Shufang Fan, Chengjun Li, Catherine Macken, Jin Hyun Kim, Masato Hatta, Gabriele Neumann, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3352917?pdf=render