A Sex-Stratified Genome-Wide Association Study of Tuberculosis Using a Multi-Ethnic Genotyping Array

A Sex-Stratified Genome-Wide Association Study of Tuberculosis Using a Multi-Ethnic Genotyping Array

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a complex disease with a known human genetic component. Males seem to be more affected than females and in most countries the TB notification rate is twice as high in males than in females. While socio-economic status, behavior and sex horm...

Full description

Bibliographic Details
Main Authors: Haiko Schurz, Craig J. Kinnear, Chris Gignoux, Genevieve Wojcik, Paul D. van Helden, Gerard Tromp, Brenna Henn, Eileen G. Hoal, Marlo Möller
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Genetics
Subjects:
tuberculosis
GWAS
sex-bias
host genetics
X chromosome
sex-stratified
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00678/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00678/full

Similar Items