Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross‐sectional diffusion tensor imaging study

Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross‐sectional diffusion tensor imaging study

Abstract Objective We aimed to investigate mutation‐specific white matter (WM) integrity changes in presymptomatic and symptomatic mutation carriers of the C9orf72, MAPT, and GRN mutations by use of diffusion‐weighted imaging within the Genetic Frontotemporal dementia Initiative (GENFI) study. Metho...

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Main Authors: Lize C. Jiskoot, Martina Bocchetta, Jennifer M. Nicholas, David M. Cash, David Thomas, Marc Modat, Sebastien Ourselin, Serge A.R.B. Rombouts, Elise G.P. Dopper, Lieke H. Meeter, Jessica L. Panman, Rick vanMinkelen, Emma L. van derEnde, Laura Donker Kaat, Yolande A.L. Pijnenburg, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, James Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B. Frisoni, Robert Laforce Jr, Elizabeth Finger, Alexandre deMendonça, Sandro Sorbi, on behalf of the Genetic Frontotemporal dementia Initiative (GENFI), Janne M. Papma, John C. vanSwieten, Jonathan D. Rohrer
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.601

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https://doi.org/10.1002/acn3.601

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