A Novel Cytosolic Isoform of Mitochondrial Trans-2-Enoyl-CoA Reductase Enhances Peroxisome Proliferator-Activated Receptor α Activity

A Novel Cytosolic Isoform of Mitochondrial Trans-2-Enoyl-CoA Reductase Enhances Peroxisome Proliferator-Activated Receptor α Activity

BackgroundMitochondrial trans-2-enoyl-CoA reductase (MECR) is involved in mitochondrial synthesis of fatty acids and is highly expressed in mitochondria. MECR is also known as nuclear receptor binding factor-1, which was originally reported with yeast two-hybrid screening as a binding protein of the...

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Bibliographic Details
Main Authors: Dong-Gyu Kim, Jae Cheal Yoo, Eunju Kim, Young-Sun Lee, Oleg V. Yarishkin, Da Yong Lee, Kun Ho Lee, Seong-Geun Hong, Eun Mi Hwang, Jae-Yong Park
Format: Article
Language:English
Published: Academya Publishing Co. 2014-06-01
Series:Endocrinology and Metabolism
Subjects:
Trans-2-enoyl-CoA reductase (NADPH)
Cytosolic mitochondrial trans-2-enoyl-CoA reductase
PPAR alpha
Alternative splicing
Mitochondrial targeting sequences
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-185.pdf

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http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-185.pdf

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