A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells

A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells

Glioblastoma harbors a dynamic subpopulation of glioblastoma stem-like cells (GSCs) that can propagate tumors in vivo and is resistant to standard chemoradiation. Identification of the cell-intrinsic mechanisms governing this clinically important cell state may lead to the discovery of therapeutic s...

Full description

Bibliographic Details
Main Authors: Diane D. Mao, Amit D. Gujar, Tatenda Mahlokozera, Ishita Chen, Yanchun Pan, Jingqin Luo, Taylor Brost, Elizabeth A. Thompson, Alice Turski, Eric C. Leuthardt, Gavin P. Dunn, Michael R. Chicoine, Keith M. Rich, Joshua L. Dowling, Gregory J. Zipfel, Ralph G. Dacey, Samuel Achilefu, David D. Tran, Hiroko Yano, Albert H. Kim
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005537

Internet

http://www.sciencedirect.com/science/article/pii/S2211124715005537

Similar Items