Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy.

To date, bovine spongiform encephalopathy (BSE) and its human counterpart, variant Creutzfeldt-Jakob disease, have been associated with a single prion strain. This strain is characterised by a unique and remarkably stable biochemical profile of abnormal protease-resistant prion protein (PrP(res)) is...

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Main Authors: Vincent Béringue, Anna Bencsik, Annick Le Dur, Fabienne Reine, Thanh Lan Laï, Nathalie Chenais, Gaëlle Tilly, Anne-Gaëlle Biacabé, Thierry Baron, Jean-Luc Vilotte, Hubert Laude
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0020112