Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety

<p>Abstract</p> <p>Background</p> <p>Melatonin is extensively used in the USA in a non-regulated manner for sleep disorders. Prolonged release melatonin (PRM) is licensed in Europe and other countries for the short term treatment of primary insomnia in patients aged 55...

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Bibliographic Details
Main Authors: Wade Alan G, Ford Ian, Crawford Gordon, McConnachie Alex, Nir Tali, Laudon Moshe, Zisapel Nava
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/8/51