Hand2 Is an Essential Regulator for Two Notch-Dependent Functions within the Embryonic Endocardium

The basic-helix-loop-helix (bHLH) transcription factor Hand2 plays critical roles during cardiac morphogenesis via expression and function within myocardial, neural crest, and epicardial cell populations. Here, we show that Hand2 plays two essential Notch-dependent roles within the endocardium. Endo...

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Bibliographic Details
Main Authors: Nathan J. VanDusen, Jose Casanovas, Joshua W. Vincentz, Beth A. Firulli, Marco Osterwalder, Javier Lopez-Rios, Rolf Zeller, Bin Zhou, Joaquim Grego-Bessa, José Luis De La Pompa, Weinian Shou, Anthony B. Firulli
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714009875