Glucocorticoids with low-dose anti-IL1 anakinra rescue in severe non-ICU COVID-19 infection: A cohort study.

<h4>Background</h4>The optimal treatment for patients with severe coronavirus-19 disease (COVID-19) and hyper-inflammation remains debated.<h4>Material and methods</h4>A cohort study was designed to evaluate whether a therapeutic algorithm using steroids with or without inter...

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Main Authors: Raphael Borie, Laurent Savale, Antoine Dossier, Jade Ghosn, Camille Taillé, Benoit Visseaux, Kamel Jebreen, Abourahmane Diallo, Chloe Tesmoingt, Lise Morer, Tiphaine Goletto, Nathalie Faucher, Linda Hajouji, Catherine Neukirch, Mathilde Phillips, Sandrine Stelianides, Lila Bouadma, Solenn Brosseau, Sébastien Ottaviani, Johan Pluvy, Diane Le Pluart, Marie-Pierre Debray, Agathe Raynaud-Simon, Diane Descamps, Antoine Khalil, Jean Francois Timsit, Francois-Xavier Lescure, Vincent Descamps, Thomas Papo, Marc Humbert, Bruno Crestani, Philippe Dieude, Eric Vicaut, Gérard Zalcman, Bichat & Kremlin-Bicêtre AP-HP COVID teams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243961