A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice.

Many viruses within the Flavivirus genus cause significant disease in humans; however, effective antivirals against these viruses are not currently available. We have previously shown that a thiopurine drug, 6-methylmercaptopurine riboside (6MMPr), inhibits replication of distantly related viruses w...

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Bibliographic Details
Main Authors: Pei-Yin Lim, Julie A Keating, Spencer Hoover, Rob Striker, Kristen A Bernard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3200352?pdf=render