c-Myb regulates transcriptional activation of miR-143/145 in vascular smooth muscle cells.

c-Myb regulates transcriptional activation of miR-143/145 in vascular smooth muscle cells.

BACKGROUND:MicroRNAs (miR) are small non-coding RNAs that regulate diverse biological functions. The bicistronic gene miR-143/145 determines cell fate and phenotype of vascular smooth muscle cells (VSMC), in part, by destabilizing Elk-1 mRNA. The transcription factor c-Myb also regulates differentia...

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Bibliographic Details
Main Authors: Mark Chandy, Masayoshi Ishida, Eric A Shikatani, Omar El-Mounayri, Lawrence Changsu Park, Talat Afroze, Tao Wang, Philip A Marsden, Mansoor Husain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6118359?pdf=render

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http://europepmc.org/articles/PMC6118359?pdf=render

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