Differentiation/Purification Protocol for Retinal Pigment Epithelium from Mouse Induced Pluripotent Stem Cells as a Research Tool.

To establish a novel protocol for differentiation of retinal pigment epithelium (RPE) with high purity from mouse induced pluripotent stem cells (iPSC).Retinal progenitor cells were differentiated from mouse iPSC, and RPE differentiation was then enhanced by activation of the Wnt signaling pathway,...

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Bibliographic Details
Main Authors: Yuko Iwasaki, Sunao Sugita, Michiko Mandai, Shigenobu Yonemura, Akishi Onishi, Shin-Ichiro Ito, Manabu Mochizuki, Kyoko Ohno-Matsui, Masayo Takahashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4934919?pdf=render