Generation of a recombinant Gag virus-like-particle panel for the evaluation of p24 antigen detection by diagnostic HIV tests.

Detection of HIV-1 p24 antigen permits early identification of primary HIV infection and timely intervention to limit further spread of the infection. Principally, HIV screening should equally detect all viral variants, but reagents for a standardised test evaluation are limited. Therefore, we aimed...

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Main Authors: Beatrice N Vetter, Vanessa Orlowski, Katrien Fransen, Christoph Niederhauser, Vincent Aubert, Marcel Brandenberger, Diana Ciardo, Günter Dollenmaier, Thomas Klimkait, Stephan Regenass, Patrick Schmid, Volkmar Schottstedt, Franziska Suter-Riniker, Sabine Yerly, Cyril Shah, Jürg Böni, Jörg Schüpbach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4208835?pdf=render