Ex Vivo Organoid Cultures Reveal the Importance of the Tumor Microenvironment for Maintenance of Colorectal Cancer Stem Cells

Ex Vivo Organoid Cultures Reveal the Importance of the Tumor Microenvironment for Maintenance of Colorectal Cancer Stem Cells

Colorectal cancer (CRC) is a heterogeneous disease, with varying clinical presentations and patient prognosis. Different molecular subgroups of CRC should be treated differently and therefore, must be better characterized. Organoid culture has recently been suggested as a good model to reflect the h...

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Bibliographic Details
Main Authors: Xingru Li, Pär Larsson, Ingrid Ljuslinder, Daniel Öhlund, Robin Myte, Anna Löfgren-Burström, Carl Zingmark, Agnes Ling, Sofia Edin, Richard Palmqvist
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
organoid
colorectal cancer
cancer stem cell
molecular profiling
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/12/4/923

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https://www.mdpi.com/2072-6694/12/4/923

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