Anion exchange chromatographic distribution of human monoclonal immunoglobulin G is determined by heavy chain subclass and level of sialic acid expression

Anion exchange chromatography is widely accepted method for purification of immunoglobulins. In this work, we used human monoclonal immunoglobulin G (IgG) with structure and solubility of normal human IgG as a model for studying chromatographic behavior of particular molecular forms of IgG. Human...

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Bibliographic Details
Main Authors: Ilić Vesna, Mojsilović Sonja, Marković Dragana, Maslovarić Irina, Milošević-Jovčić Nadežda
Format: Article
Language:English
Published: Association of Chemical Engineers of Serbia 2012-01-01
Series:Hemijska Industrija
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0367-598X/2012/0367-598X1200011I.pdf