Steroid 21-hydroxylase gene variants and late-life depression

Steroid 21-hydroxylase gene variants and late-life depression

Abstract Objectives A feature of late-life depression is alterations of the stress hormone system. The CYP21A2 gene encodes for the steroid 21-hydroxylase enzyme which is required for the biosynthesis of mineralocorticoids and glucocorticoids, two main components of the stress response in humans. Va...

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Bibliographic Details
Main Authors: Marie-Laure Ancelin, Joanna Norton, Karen Ritchie, Isabelle Chaudieu, Joanne Ryan
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Research Notes
Subjects:
Late-life depression
Older adults
Population-based study
Stress
Corticosteroids
Single-nucleotide polymorphisms
Online Access:https://doi.org/10.1186/s13104-021-05616-6

Internet

https://doi.org/10.1186/s13104-021-05616-6

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