Effect of Ischemic Preconditioning and Postconditioning on Exosome-Rich Fraction microRNA Levels, in Relation with Electrophysiological Parameters and Ventricular Arrhythmia in Experimental Closed-Chest Reperfused Myocardial Infarction

Effect of Ischemic Preconditioning and Postconditioning on Exosome-Rich Fraction microRNA Levels, in Relation with Electrophysiological Parameters and Ventricular Arrhythmia in Experimental Closed-Chest Reperfused Myocardial Infarction

We investigated the antiarrhythmic effects of ischemic preconditioning (IPC) and postconditioning (PostC) by intracardiac electrocardiogram (ECG) and measured circulating microRNAs (miRs) that are related to cardiac conduction. Domestic pigs underwent 90-min. percutaneous occlusion of the mid left a...

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Bibliographic Details
Main Authors: Andreas Spannbauer, Denise Traxler, Dominika Lukovic, Katrin Zlabinger, Johannes Winkler, Alfred Gugerell, Péter Ferdinandy, Derek J. Hausenloy, Noemi Pavo, Maximilian Y. Emmert, Simon P. Hoerstrup, Andras Jakab, Mariann Gyöngyösi, Martin Riesenhuber
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
miRNA
extracellular vesicles
exosomes
exosome-rich fraction
ischemic preconditioning
ischemic postconditioning
acute myocardial infarction
cardiac electrophysiology
electrocardiography
ventricular arrhythmia
reperfusion arrhythmia
ischemia-reperfusion injury
Online Access:https://www.mdpi.com/1422-0067/20/9/2140

Internet

https://www.mdpi.com/1422-0067/20/9/2140

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