The vasculature in HFpEF vs HFrEF: differences in contractile protein expression produce distinct phenotypes

Both heart failure with reduced (HFrEF) and preserved (HFpEF) ejection fraction are associated with abnormalities of the vasculature, including a resting vasoconstriction and a decrease in sensitivity to nitric oxide (NO) mediated vasodilation. Vascular tone is controlled by the expression and activ...

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Bibliographic Details
Main Authors: Melissa A. Lyle, Mohamad S. Alabdaljabar, Young Soo Han, Frank V. Brozovich
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584401936788X