Glycoconjugate vaccine containing Escherichia coli O157:H7 O-antigen linked with maltose-binding protein elicits humoral and cellular responses.

Glycoconjugate is one of the most efficacious and safest vaccines against bacterial pathogens. Previous studies of glycoconjugates against pathogen E. coli O157:H7 focused more on the humoral responses they elicited. However, little was known about their cellular responses. In this study, we exploit...

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Bibliographic Details
Main Authors: Zhongrui Ma, Huajie Zhang, Wenjing Shang, Faliang Zhu, Weiqing Han, Xueer Zhao, Donglei Han, Peng George Wang, Min Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4138118?pdf=render