Targeted next generation sequencing as a tool for precision medicine

Targeted next generation sequencing as a tool for precision medicine

Abstract Background Targeted next-generation sequencing (NGS) enables rapid identification of common and rare genetic variation. The detection of variants contributing to therapeutic drug response or adverse effects is essential for implementation of individualized pharmacotherapy. Successful applic...

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Bibliographic Details
Main Authors: Markus Gulilat, Tyler Lamb, Wendy A. Teft, Jian Wang, Jacqueline S. Dron, John F. Robinson, Rommel G. Tirona, Robert A. Hegele, Richard B. Kim, Ute I. Schwarz
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Medical Genomics
Subjects:
Targeted exome sequencing
Next generation sequencing
Pharmacogenes
Copy number variation
In silico prediction
Online Access:http://link.springer.com/article/10.1186/s12920-019-0527-2

Internet

http://link.springer.com/article/10.1186/s12920-019-0527-2

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