Mu-seq: sequence-based mapping and identification of transposon induced mutations.

Mutations tagged by transposon insertions can be readily mapped and identified in organisms with sequenced genomes. Collections of such mutants allow a systematic analysis of gene function, and can be sequence-indexed to build invaluable resources. Here we present Mu-seq (Mutant-seq), a high-through...

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Bibliographic Details
Main Authors: Donald R McCarty, Sue Latshaw, Shan Wu, Masaharu Suzuki, Charles T Hunter, Wayne T Avigne, Karen E Koch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3806735?pdf=render