CD4+ T-cell priming as biomarker to study immune response to preventive vaccines

T-cell priming is a critical event in the initiation of the immune response to vaccination since it deeply influences both the magnitude and the quality of the immune response induced. CD4+ T-cell priming, required for the induction of high-affinity antibodies and immune memory, represents a key tar...

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Bibliographic Details
Main Authors: Annalisa eCiabattini, Elena ePettini, Donata eMedaglini
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00421/full