A protocol for the systematic review and meta-analysis of thigmotactic behaviour in the open field test in rodent models associated with persistent pain

Objective Thigmotaxis is an innate predator avoidance behaviour of rodents and is enhanced when animals are under stress. It is characterised by the preference of a rodent to seek shelter, rather than expose itself to the aversive open area. The behaviour has been proposed to be a measurable constru...

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Bibliographic Details
Main Authors: Jan Vollert, Xue Ying Zhang, Andrew SC Rice
Format: Article
Language:English
Published: BMJ Publishing Group 2021-07-01
Series:BMJ Open Science
Online Access:https://openscience.bmj.com/content/5/1/e100135.full