Cardiac regeneration using pluripotent stem cells—Progression to large animal models

Pluripotent stem cells (PSCs) have indisputable cardiomyogenic potential and therefore have been intensively investigated as a potential cardiac regenerative therapy. Current directed differentiation protocols are able to produce high yields of cardiomyocytes from PSCs and studies in small animal mo...

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Bibliographic Details
Main Authors: James J.H. Chong, Charles E. Murry
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114000786