Polyhexamethylene Guanidine Phosphate Induces Apoptosis through Endoplasmic Reticulum Stress in Lung Epithelial Cells

Polyhexamethylene Guanidine Phosphate Induces Apoptosis through Endoplasmic Reticulum Stress in Lung Epithelial Cells

Airway epithelial cell death contributes to the pathogenesis of lung fibrosis. Polyhexamethylene guanidine phosphate (PHMG-p), commonly used as a disinfectant, has been shown to be strongly associated with lung fibrosis in epidemiological and toxicological studies. However, the molecular mechanism u...

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Bibliographic Details
Main Authors: Mi Ho Jeong, Mi Seon Jeon, Ga Eun Kim, Ha Ryong Kim
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
PHMG-p
ER stress
apoptosis
lung fibrosis
Online Access:https://www.mdpi.com/1422-0067/22/3/1215

Internet

https://www.mdpi.com/1422-0067/22/3/1215

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