Tonically Active α2 Subunit-Containing Glycine Receptors Regulate the Excitability of Striatal Medium Spiny Neurons

Tonically Active α2 Subunit-Containing Glycine Receptors Regulate the Excitability of Striatal Medium Spiny Neurons

Medium spiny neurons (MSNs) of the dorsal striatum represent the first relay of cortico–striato–thalamic loop, responsible for the initiation of voluntary movements and motor learning. GABAergic transmission exerts the main inhibitory control of MSNs. However, MSNs also express chloride-permeable gl...

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Bibliographic Details
Main Authors: Svetlana M. Molchanova, Joris Comhair, Deniz Karadurmus, Elisabeth Piccart, Robert J. Harvey, Jean-Michel Rigo, Serge N. Schiffmann, Bert Brône, David Gall
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
dorsal striatum
medium spiny neurons
glycine receptors
tonic current
excitability
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00442/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00442/full

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