Mechanistic role of antioxidants in rescuing delayed gastric emptying in high fat diet induced diabetic female mice

Mechanistic role of antioxidants in rescuing delayed gastric emptying in high fat diet induced diabetic female mice

Diabetic gastroparesis (DG) exhibits delayed gastric emptying (GE) due to impaired gastric non-adrenergic, non-cholinergic (NANC) relaxation. These defects are due to loss or reduction of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) that causes reduced expression and/or dimerization of neurona...

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Bibliographic Details
Main Authors: Chethan Sampath, Derek Wilus, Mohammad Tabatabai, Michael L. Freeman, Pandu R. Gangula
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cinnamaldehyde
Curcumin
Nitrergic relaxation
Gastric emptying
Inflammation
Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221001554

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http://www.sciencedirect.com/science/article/pii/S0753332221001554

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