Cigarette Smoke Extract Stimulates MMP-2 Production in Nasal Fibroblasts via ROS/PI3K, Akt, and NF-κB Signaling Pathways

Cigarette Smoke Extract Stimulates MMP-2 Production in Nasal Fibroblasts via ROS/PI3K, Akt, and NF-κB Signaling Pathways

Cigarette smoke exposure has been shown to be associated with chronic rhinosinusitis and tissue remodeling. The present study aimed to investigate the effects of cigarette smoke extract (CSE) on matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) production in nasal fibro...

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Bibliographic Details
Main Authors: Joo-Hoo Park, Jae-Min Shin, Hyun-Woo Yang, Tae Hoon Kim, Seung Hoon Lee, Heung-Man Lee, Jae-Gu Cho, Il-Ho Park
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
cigarette smoke extract
nasal fibroblasts
tissue inhibitor of metalloproteinases
matrix metalloproteinase
steroids
Online Access:https://www.mdpi.com/2076-3921/9/8/739

Internet

https://www.mdpi.com/2076-3921/9/8/739

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