Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome.

Sjögren's syndrome (SS) is a chronic, autoimmune exocrinopathy that leads to severe dryness of the mouth and eyes. Exocrine function is highly regulated by neuronal mechanisms but little is known about the link between chronic inflammation, innervation and altered exocrine function in the disea...

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Bibliographic Details
Main Authors: Feeling Y Chen, Albert Lee, Shaokui Ge, Sara Nathan, Sarah M Knox, Nancy A McNamara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5605119?pdf=render