Cellular Senescence in Brain Aging

Cellular Senescence in Brain Aging

Aging of the brain can manifest itself as a memory and cognitive decline, which has been shown to frequently coincide with changes in the structural plasticity of dendritic spines. Decreased number and maturity of spines in aged animals and humans, together with changes in synaptic transmission, may...

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Bibliographic Details
Main Authors: Ewa Sikora, Anna Bielak-Zmijewska, Magdalena Dudkowska, Adam Krzystyniak, Grazyna Mosieniak, Malgorzata Wesierska, Jakub Wlodarczyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
autophagy
brain aging
cellular senescence
cognitive impairment
neuroinflammation
neuronal plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.646924/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.646924/full

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