Immunogenicity of HIV-1-Based Virus-Like Particles with Increased Incorporation and Stability of Membrane-Bound Env

Immunogenicity of HIV-1-Based Virus-Like Particles with Increased Incorporation and Stability of Membrane-Bound Env

An optimal prophylactic vaccine to prevent human immunodeficiency virus (HIV-1) transmission should elicit protective antibody responses against the HIV-1 envelope glycoprotein (Env). Replication-incompetent HIV-1 virus-like particles (VLPs) offer the opportunity to present virion-associated Env wit...

Full description

Bibliographic Details
Main Authors: Christopher A. Gonelli, Hannah A. D. King, Charlene Mackenzie, Secondo Sonza, Rob J. Center, Damian F. J. Purcell
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Vaccines
Subjects:
HIV-1
virus-like particle
VLP
mature form
Env incorporation
SOSIP
Online Access:https://www.mdpi.com/2076-393X/9/3/239

Internet

https://www.mdpi.com/2076-393X/9/3/239

Similar Items