Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

Objective: Parental nutrition and lifestyle impact the metabolic phenotype of the offspring. We have reported that grandpaternal chronic high-fat diet (HFD) transgenerationally impairs glucose metabolism in subsequent generations. Here we determined whether grandpaternal diet transgenerationally imp...

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Bibliographic Details
Main Authors: Petter S. Alm, Thais de Castro Barbosa, Romain Barrès, Anna Krook, Juleen R. Zierath
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Molecular Metabolism
Subjects:
Skeletal muscle
Epigenetics
Unfolded protein response (UPR)
Lipodome
Transcriptome
Activation of the stress sensor (ATF)
Online Access:http://www.sciencedirect.com/science/article/pii/S221287781730340X

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http://www.sciencedirect.com/science/article/pii/S221287781730340X

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