Intranasal delivery of cationic PLGA nano/microparticles-loaded FMDV DNA vaccine encoding IL-6 elicited protective immunity against FMDV challenge.

Intranasal delivery of cationic PLGA nano/microparticles-loaded FMDV DNA vaccine encoding IL-6 elicited protective immunity against FMDV challenge.

Mucosal vaccination has been demonstrated to be an effective means of eliciting protective immunity against aerosol infections of foot and mouth disease virus (FMDV) and various approaches have been used to improve mucosal response to this pathogen. In this study, cationic PLGA (poly(lactide-co-glyc...

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Bibliographic Details
Main Authors: Gang Wang, Li Pan, Yongguang Zhang, Yonglu Wang, Zhongwang Zhang, Jianliang Lü, Peng Zhou, Yuzhen Fang, Shoutian Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3216981?pdf=render

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http://europepmc.org/articles/PMC3216981?pdf=render

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