Role of Endothelium in Doxorubicin-Induced Cardiomyopathy
Summary: The clinical use of doxorubicin in cancer is limited by cardiotoxic effects that can lead to heart failure. Whereas earlier work focused on the direct impact of doxorubicin on cardiomyocytes, recent studies have turned to the endothelium, because doxorubicin-damaged endothelial cells can tr...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-12-01
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Series: | JACC: Basic to Translational Science |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452302X18301396 |