CD4 T-cell subsets in Malaria: TH1/TH2 revisited

CD4+ T cells have been shown to play a central role in immune control of infection with Plasmodium parasites. At the erythrocytic stage of infection, IFN-γ production by CD4+ T cells and CD4+ T-cell help for the B-cell response are required for control and elimination of infected red blood cells. C...

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Bibliographic Details
Main Authors: Damian ePerez-Mazliah, Jean eLanghorne
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Immunology
Subjects:
Th1
th2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00671/full